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KMID : 0361920220520010075
Korean Journal of Orthodontics
2022 Volume.52 No. 1 p.75 ~ p.79
Micro-computed tomographic evaluation of the effect of fluoride agents on white spot lesions: An in vitro study
Hong Sook-Chan

Lee Dong-Yul
Kim Yae-Jin
Abstract
Objective: To investigate remineralizing effect of three fluoride regimens on artificially demineralized enamel around orthodontic bracket by analyzing mineral density (MD) acquired from micro-computed tomography (micro-CT).

Methods: Forty-eight bracket bonded bovine incisors were prepared to create demineralized enamel (DE) surface. The samples were divided into four groups according to the fluoride regimen: 1) no fluoridation, 2) 1.23% acidulated phosphate fluoride (APF) gel, 3) fluoridated toothpaste, and 4) 0.05% sodium fluoride mouthwash. Micro-CT was scanned after demineralization (T0), and 2 weeks (T1) and 4 weeks (T2) of fluoridation.

Results: APF gel showed highest remineralization of DE during T1?T0 interval among the groups (p < 0.05); followed by toothpaste, mouthwash and no fluoridation. APF gel and toothpaste demonstrated significant increase in MD after 4 weeks of application (p < 0.05).

Conclusions: Remineralization effects of three fluoride regimens were depicted through micro-CT analysis, of which APF gel was most effective.
KEYWORD
Cariology, Fluoride, Micro-computed tomography
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